Atopic eczema usually begins in infancy (45% of cases). From the first six months of life), 70 percent. Children are affected before age 5. About 60 percent of the children will become adults. Adolescent AE, though it may be up to 50%. Further onset in adulthood.It’s important to keep that in mind. Adults may show AE and this. 10% of secondary nursing cases. The etiology of AE is complex, and both involve. Genetic and environmental factors.6 pairs and family. Studies have shown that genetic factors play an important role. Vulnerable to AE and other atopic diseases. Show clustering in families and parents’ children. Risk ratio for AE occurrence. Children whose parents have hay fever or asthma.Of the eight. The discovery of zero mutation in filaggrin is. Correlation with AE has proved to be a major breakthrough. In our understanding of the genetic basis. Filaggrin plays a key role in epidermal barrier. Dysfunction, and the resulting dysfunction. Mutations in filaggrin genes may increase. Exposure to an allergen results in an overreaction to an allergen. Environmental factors and IgE induction. Autoantibodies.
The study of floating population has been done. The importance of environmental factors is explained. For example, children who move to the United States from Jamaica. In London, a-shares are twice as likely to rise. The occurrence of AE is related to city and industry. Environment, higher socioeconomic status and smaller. Family size.These findings have led to many different results. Hypothesis about AE mechanism. Atopic eczema is characterized by ambiguity Erythema with edema, blisters, tears Skin thickening (moss-like change) during acute phase Chronic phase .AE usually starts with babies Cheeks can turn red and sore. As the AE progression, which may affect normal bending sites, So patients should be examined behind the knee, elbow fold and neck fold.a When a baby is weaned, AE usually erupts. At this time, children like to explore new foods. And tend to put these on your face.Many food Can the stimulus be combined with this dribble Causing more severe facial and neck flares, Especially in the neck folds of a well-fed child.hand Another website checks because of many kindergarten activities Play with stimulants like sand, Paint, mimic clay, water or bubbles.In this Time and scratching may have become habitual, Common, accessible parts are the wrist and Ankle, occlusion and more protected areas, etc The abdomen and back are often clearer because of the diaper area. However, children with AE are more severely stimulated Contact dermatitis in napkin area Direct contact with soiled diapers.This tends to Not so much trouble for the modern introduction Absorbent disposable diapers. Epidermal barrier dysfunction affects all skin, and it does It is important to check for dry skin that is not eczema. Superlinear palm trees were found in some cases Related to filaggrin gene mutation.